Aging Well, Sleeping Efficiently (AgeWise)
AgeWise Principal Investigators
Program Principal Investigator Timothy H. Monk, PhD, D.Sc.
Program Co-Principal Investigator Daniel J. Buysse, M.D.
AgeWise Program Study Description
The current study focuses on seniors with and without insomnia; the effect of a behavioral therapy treatment on seniors with insomnia; the causes of insomnia in seniors and the differences between those with insomnia and those who sleep well. Our aim is to provide a better understanding of the factors underlying insomnia, so that this serious health problem can be successfully treated. The principal investigator is Timothy Monk, Ph.D.,D.Sc.
For more information, call 1-866-647-8283 (toll-free) or e-mail AgeWise@upmc.edu.
Men and women age 60 and older who have had chronic insomnia for at least 6 months, characterized by and difficulty staying asleep. Participants must be in stable medical condition; have no history of a neurologic disorder or stroke, not be taking medications for sleep or depression, and not have been diagnosed with or treated for sleep apnea.
Good-sleeping older adults meeting similar criteria will also be recruited (see below).
Men and women under 60 years of age; history of neurologic disorder or stroke, taking medications for sleep or depression, diagnosed or treated for sleep apnea. Certain other exclusionary criteria (e.g., metal in the body) also apply to specific laboratory evaluations.
Brain function in older adults with and without insomnia, and the changes in brain function that occur after a behavioral treatment of the insomnia. The research covers several different domains, including brain electrical activity (EEG), 24-hour biological rhythms, reactions to stress, imaging of brain function, and genetics related to sleep.
Those who are eligible for the study will be given a detailed health and sleep screening. If they pass that screening, they will then participate in one of three different laboratory evaluations, each lasting several days, which will be conducted twice: Once before, and once after behavioral treatment for insomnia. These evaluations will be supplemented by data obtained from diaries, questionnaires and interviews.
Good-sleeping older adults will only participate in the laboratory evaluation once.
Participants are compensated between $500 and $600 depending upon the laboratory evaluation to which they are assigned. We are also recruiting good sleeping seniors meeting similar criteria. Good sleeping seniors only participate once in the laboratory evaluation and do not receive treatment. They are compensated between $250 and $300 depending upon the laboratory evaluation to which they are assigned.